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Tyloxapol – Specialized non-ionic surfactant, optimizing solubility and applications in ophthalmic and respiratory medications

Tyloxapol – Superior surfactant, wetting agent, and solubilizer for ophthalmic and respiratory formulations. Contact Biorich now!

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    1. General introduction to Tyloxapol

    Tyloxapol is a non-ionic liquid polymer of the alkyl aryl polyether alcohol type, acting as a highly effective surfactant and wetting agent in the pharmaceutical industry.

    The material is manufactured by reputable international standard pharmaceutical excipient manufacturers. With high safety and low toxicity, Tyloxapol is specially designed to improve the solubility of poorly soluble drugs while reducing surface tension in solutions and suspensions, especially for formulations requiring high mildness to mucous membranes.

    2. Information on Tyloxapol raw material

    • Material Name: Tyloxapol
    • Material Group: Pharmaceutical Excipients / Surfactants, wetting agents, solubilizers.
    • Function: Non-ionic surfactant, solubility enhancer, dispersing agent, mucolytic agent.
    • Chemical Composition: Polymer of 4-(1,1,3,3-tetramethylbutyl)phenol with formaldehyde and oxirane.
    • Form: Viscous liquid, pale yellow to amber, with a mild odor.
    • Solubility: Highly soluble in water and many organic solvents.
    • Quality Standards: Meets current international Pharmacopoeia standards (USP/Ph.Eur).

    The special material is strictly controlled for:

    • Free Impurities: Ensures the level of impurities (such as ethylene oxide and 1,4-dioxane) is kept to the strictest minimum for absolute safety in direct respiratory or ophthalmic formulations.
    • pH and Surface Tension: Strictly controlled to optimize the wetting ability of biological tissue surfaces and maintain the stability of emulsion/suspension systems.

    3. Advantages of Tyloxapol raw material

    • Excellent surface activity: Significantly reduces surface tension, helping the drug solution to spread, adhere, and penetrate better on physiological mucous membranes (e.g., ocular mucosa, respiratory mucous membranes).
    • High stability and compatibility: Its non-ionic nature gives Tyloxapol excellent compatibility with various active pharmaceutical ingredients (APIs) and excipient systems without causing precipitation or incompatibility.
    • Superior biological safety: Causes very little irritation to mucous membranes compared to many other surfactants, making it safe for particularly sensitive tissue areas.
    • Reasonable cost - Stable supply: Supplied by leading partners, providing a high-quality excipient solution at a competitive cost for pharmaceutical plants.

    4. Applications of Tyloxapol

    In pharmaceuticals (Core applications):

    • Eye drops (Ophthalmology): Used as a wetting and dispersing agent in ophthalmic suspensions or solutions, helping drug particles to distribute evenly, preventing agglomeration, and soothing the eyes to reduce irritation.
    • Respiratory and inhalation medications: Acts as a mucolytic agent in aerosol solutions used to treat respiratory diseases, while also enhancing the solubility of bronchodilators.
    • Injections and emulsions: Acts as an emulsifier or co-emulsifier in some intravenous lipid emulsion drug delivery systems.

    In medical devices and healthcare:

    • Applied in contact lens cleaning and hygiene solutions due to its gentle cleansing ability and effective removal of lipid/protein deposits on the lens surface.

    5. Commercial products using Tyloxapol

    6. Product contact information

    For more information on the supply chain, technical specifications of Tyloxapol, or to place an order, please contact us:

    • Consulting Hotline: +84 (0) 834 560 500
    • Email: director@biorichgroup.com
    • Website:www.biorichgroup.com
    • Sample/COA Request: Please contact us via email to request a sample and the latest Certificate of Analysis (COA) of the material.
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