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Simethicone 100% Oil – Effective anti-foaming and anti-flatulence active ingredient from India

1. General introduction to Simethicone 100% Oil

Simethicone 100% Oil is a high-molecular-weight silicone-based compound, an optimal combination of Polydimethylsiloxane and Colloidal Silicon Dioxide. This active ingredient acts as an effective mechanical anti-foaming agent, helping to reduce the surface tension of gas bubbles in the stomach and intestines, causing them to rupture and be easily eliminated.

The raw material is manufactured by Nitika Pharmaceutical Specialities Pvt. Ltd. (India), a world-leading manufacturer of specialized excipients and active ingredients with international GMP certification. With advanced technological processes, Nitika's Simethicone 100% Oil achieves optimal purity, absolute consistency between batches, and fully meets the most stringent global pharmacopoeial standards.

2. Raw material information of Simethicone 100% Oil

  • Raw material name: Simethicone 100% Oil
  • Manufacturer: Nitika Pharmaceutical Specialities Pvt. Ltd.
  • Origin: India
  • Material group: Active Pharmaceutical Ingredient (API) / Medical excipient.
  • Function: Anti-foaming agent, surface defoamer, treatment of flatulence and bloating.
  • Chemical composition: Mixture of Polydimethylsiloxane (silicone fluid) and Silicon Dioxide.
  • Appearance: Viscous oily liquid, greyish-white or translucent.
  • Solubility: Practically insoluble in water and alcohol (ethanol); disperses well in emulsion systems.
  • Quality standards: Meets United States Pharmacopeia (USP), European Pharmacopoeia (EP), and British Pharmacopoeia (BP) standards.

The material is strictly controlled for:

  • Dispersion stability: Precise ratio of silica to polydimethylsiloxane ensures the material does not separate during formulation and storage.
  • Heavy metals and microbiological indices: Meets strict microbiological standards for oral preparations, ensuring absolute safety.

3. Advantages of Simethicone 100% Oil from Nitika

  • Superior mechanical anti-foaming efficacy: Rapid physical action directly in the gastrointestinal tract without being absorbed into the bloodstream, safe for all users, including infants.
  • Outstanding formulation properties: High chemical inertness, easily combined and compatible with antacids, digestive enzymes, or other antispasmodic active ingredients.
  • Reasonable cost - Stable supply: Manufactured in India by Nitika, offering highly competitive pricing compared to European or American sources, providing an effective solution for manufacturing plants to optimize costs.

4. Applications of Simethicone 100% Oil

  • In pharmaceuticals: Used as the main active ingredient (API) for medications treating flatulence, bloating, and indigestion in the form of soft capsules, chewable tablets, oral drops (for children), and oral suspensions. Often combined in antacid gastric formulations.
  • In clinical medicine: Used as an anti-foaming agent prior to gastroscopy and colonoscopy to clear gas bubbles and enhance visibility for endoscopy.

5. Commercial products using Simethicone

6. Product contact information

For more information on the supply chain, technical specifications of Simethicone 100% Oil, or to place an order, please contact us:

  • Consulting Hotline: +84 (0) 834 560 500
  • Email: director@biorichgroup.com
  • Website:www.biorichgroup.com
  • Sample/COA Request: Please contact us via email to request samples and the latest Certificate of Analysis (COA) for the raw material from the manufacturer Nitika Pharmaceutical Specialities Pvt. Ltd.

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