Silicified Microcrystalline Cellulose – Premium direct compression excipient from India

1. General Introduction to Silicified Microcrystalline Cellulose

Silicified Microcrystalline Cellulose (SMCC) is a co-processed excipient created from the optimal combination of Microcrystalline Cellulose (MCC) and Colloidal Silicon Dioxide (CSD). This ingredient stands out with excellent flow properties, high compressibility, and uniform particle size distribution. SMCC is widely used as a filler and binder in direct compression tableting.

The raw material is manufactured by Gangwal Healthcare Pvt Ltd (India), a reputable manufacturer of specialized excipients with international GMP certification. With advanced technological processes, Gangwal's SMCC achieves optimal purity, strict control of quality indicators, absolute consistency between production batches, and fully meets the most stringent pharmacopoeial standards.

2. Raw Material Information of Silicified Microcrystalline Cellulose

• Raw material name: Silicified Microcrystalline Cellulose (SMCC)
• Manufacturer: Gangwal Healthcare Pvt Ltd
• Origin: India
• Material group: Pharmaceutical Excipients.
• Function: Filler, binder, flow enhancer for direct compression tableting and capsule filling.
• Chemical composition: Co-processed mixture of microcrystalline cellulose and colloidal silicon dioxide.
• Appearance: White, odorless powder with excellent flowability.
• Solubility: Practically insoluble in water, dilute acids, and most organic solvents.
• Quality standards: Meets United States Pharmacopeia (USP/NF) and European Pharmacopoeia (EP) standards.

The material is strictly controlled for:

• Particle size distribution: Optimized to prevent segregation during blending and tableting.
• Heavy metals and microbiological indices: Meets strict standards for oral preparations.

3. Advantages of Silicified Microcrystalline Cellulose from Gangwal

• Superior compressibility and flowability: Significantly improved compared to simple physical mixing of MCC and CSD, helping tablets achieve high hardness and low friability without requiring excessive compression force.
• Optimized direct compression process: Minimizes punch sticking, prevents powder blend segregation, and ensures perfect content uniformity, especially effective for low-dose or difficult-to-compress active pharmaceutical ingredients (APIs).
• Outstanding formulation properties: High stability, compatible with most common pharmaceutical active ingredients, and protects moisture-sensitive APIs.
• Reasonable cost - Stable supply: Manufactured in India by Gangwal, offering optimal competitive pricing, providing an effective solution for manufacturing plants to optimize product costs.

4. Applications of Silicified Microcrystalline Cellulose

• In pharmaceuticals: The core excipient for direct compression tablet, capsule, chewable tablet, and dispersible tablet formulations.
• In health supplements: Used as a filler and binder in nutritional, vitamin, and mineral supplement tablets requiring high hardness and rapid disintegration.

5. Commercial Products Using Silicified Microcrystalline Cellulose

6. Product Contact Information

For more information on the supply chain, technical specifications of Silicified Microcrystalline Cellulose, or to place an order, please contact us:

• Consulting Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website:www.biorichgroup.com
• Sample/COA Request: Please contact us via email to request samples and the latest Certificate of Analysis (COA) for the raw material from the manufacturer Gangwal Healthcare Pvt Ltd.