Hydrogenated castor oil – A lubricant and sustained release agent

1. General Introduction to Hydrogenated Castor Oil

Hydrogenated castor oil is a hydrogenated product derived from the seed oil of the castor plant. It is used in pharmaceutical formulations as a lubricant, a release-modifying agent in sustained-release tablets, and a consistency modifier in soft gelatin capsules and topical creams.

2. Characteristics of Hydrogenated Castor Oil

• Name: Hydrogenated Castor Oil
• Other Names: Castor Wax, Hydrogenated Castor Oil
• Origin: China
• Main Composition: A mixture of fatty acid triglycerides, primarily 12-hydroxystearic acid formed by complete hydrogenation.
• Physical Form: Fine powder or hard waxy flakes, white to slightly yellowish-white.
• Key Properties: High melting point, chemically inert, and free of metal ion radicals.
• Solubility: Practically insoluble in water and 96% ethanol; soluble in chloroform, ether, and other organic solvents upon heating.
• Quality Standards: Complies with international pharmacopoeia standards: USP/NF, EP, BP, ChP.

Standard Control Parameters:

• Identification and fatty acid composition (especially 12-hydroxystearic acid content).
• High and stable melting range.
• Iodine value (controlled at a very low level to ensure complete hydrogenation), acid value, and hydroxyl value.
• Limits for heavy metals, nickel (residual catalyst), and sulfated ash.
• Microbial limits tailored for pharmaceutical manufacturing applications.

3. Key Advantages Hydrogenated Castor Oil

• Applicable to various tablet manufacturing processes such as direct compression, wet granulation, hot-melt extrusion, and solid dispersion systems.
• Lipid-based lubricant that provides a smooth, glossy tablet surface and reduces ejection force during tablet compression.
• High melting point lubricant, suitable for heat-sensitive active ingredients such as Clopidogrel.
• Free from metallic taste and non-reactive, ensuring broad compatibility with other formulation components.
• Improves disintegration, dissolution, and enhances bioavailability in microemulsion and nanodrug delivery systems. 
• Product complies with USP/EP/BP
• The manufacturer has EXCIPACT GMP Certificate for Pharma application

4. Applications of Hydrogenated Castor Oil 

In Pharmaceuticals

• Lubricant and anti-adherent excipient
• Matrix-forming agent for sustained-release tablets
• Thickening and suspending agent for soft gelatin capsule fillings
• Enhances stability and bioavailability in microemulsions, solid dispersions, and nanodrug delivery systems
• Improves consistency and bioavailability in topical creams and ointments

In Cosmetics and Personal Care

• Lipsticks and sticks form products: Enhances mechanical hardness, provides a natural gloss, and prevents breaking, melting, or "sweating" caused by environmental temperatures.
• Creams and emulsions: Stabilizes emulsion systems, delivers a rich and smooth product texture, improves skin retention and absorption, and enhances moisture retention on the skin surface.

5. Commercial Products using Hydrogenated Castor Oil

6. Product Contact Information

For further information regarding the supply chain and technical specifications of Hydrogenated Castor Oil or to place an order, please contact:

• Consultation Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website:www.biorichgroup.com
• Sample/COA Requests: Please contact us via email to receive product samples, Certificates of Analysis (COA), and the latest technical documentation directly from the manufacturer.