Edetate Sodium – Chelating agent supporting pH and preservative system stability
1. General introduction to Edetate Sodium
Edetate Sodium is a widely used chelating agent in pharmaceuticals, cosmetics, and food products, valued for its ability to bind with metal ions and stabilize formulation systems. This raw material is typically applied to control free metal ions that can catalyze oxidation reactions, thereby helping to mitigate discoloration, prevent loss of active ingredient potency and enhance the shelf-life stability of finished products during storage.
In modern formulations, Edetate Sodium is highly regarded for its ability to maintain pH stability, boost the efficacy of preservative systems, and improve the stability of oxidation-sensitive active ingredients such as Vitamin C, peptides, or botanical extracts.
The material is manufactured by Sujata Nutri-Pharma Pvt. Ltd. (India), a company specializing in the supply of high-quality pharmaceutical ingredients, nutritional components, and excipients. Complying with USP/BP/EP standards, this material helps manufacturers fulfill rigorous technical requirements for high end product lines.
2. Active ingredient of Edetate Sodium
Material Name: Edetate Sodium
Alternative Name: Edetate Sodium
Manufacturer:Sujata Nutri-Pharma Pvt. Ltd.
Origin: India
Material Group: Chelating Agent / Stabilizing Agent
Function:Chelates metal ions, enhances formulation stability, boosts preservative system efficacy, and inhibits oxidation.
Chemical Name: Disodium Ethylenediaminetetraacetate
Physical State: White crystalline powder
Solubility: Highly soluble in water
Quality Standards:USP, BP, EP, or equivalent standards.
Critical quality control parameters include:
Purity
Assay
Heavy metals / Metal impurities
pH of solution
Microbiological limits
Chemical stability
3. Key advantages of Edetate Sodium
Excellent metal chelating capacity:Effectively controls free metal ions in aqueous formulation systems.
Stabilization of oxidation sensitive actives: Mitigates oxidation risk and reduces the degradation rate of active ingredients.
Preservative synergy: Synergistically enhances the efficacy of various preservative systems.
pH stability maintenance: Ideal for formulations requiring a strictly controlled and stable pH environment.
Broad formulation compatibility: Performs exceptionally well in serums, gels, lotions, solutions, and emulsions.
High water solubility: Facilitates seamless compounding and large-scale industrial manufacturing.
Compliance with international quality standards:Meets USP/BP/EP specifications, making it fully suitable for premium pharmaceutical and cosmetic products.
4. Applications of Edetate Sodium
In pharmaceuticals
Oral solutions: Controls metal ions and enhances the stability of oxidation-sensitive actives in liquid formulation systems.
Ophthalmic drops: Utilized in ophthalmic formulations to safeguard structural stability and enhance preservative efficacy.
Topical pharmaceutical solutions: Inhibits metal-catalyzed oxidation in aqueous gels, lotions, and topical solutions.
Specialized liquid formulations: Applied to manage metal ion interactions in specialized formulas requiring high stability profiles.
In cosmetics
Vitamin C & antioxidant serums: Stabilizes highly vulnerable active ingredients such as Vitamin C, peptides, and botanical extracts.
Creams & lotions: Improves overall emulsion stability and optimizes the performance of the preservative system.
Cleansers & Toners: Counteracts the negative effects of metal ions in water systems to maintain the product's organoleptic (sensory) stability.
Hair Care Products: Stabilizes formulations and enhances the performance efficiency of functional ingredients.
In food products
Beverages & Processed Foods:Utilized in regulatory-compliant formulation systems to stabilize color and prevent metal-induced oxidation.
Nutritional Supplements: Regulates metal ion interactions in supplement formulas containing oxidation-sensitive vitamins and minerals.
5. Commercial products using Edetate Sodium
6. Product contact information
For further information regarding our supply chain, technical specifications for Edetate Sodium, or to place an order, please contact us:
Edetate Sodium is a chelating agent used in pharmaceutical, cosmetic, and food formulations to support pH stability, control metal ions, and enhance preservative system performance. Suitable for serums, solutions, gels, and oxidation-sensitive formulations.
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