1. General introduction to Dimethicone 

Dimethicone is a biologically inert siloxane polymer widely utilized in pharmaceutical, cosmetic, and personal care applications as an antifoaming excipient, lubricant, and emollient for topical formulations.

Owing to its hydrophobic characteristics, excellent stability profile, and superior film-forming properties, Dimethicone has become a preferred excipient for premium pharmaceutical and cosmetic formulations requiring optimized sensory performance and long-term formulation stability.

Dimethicone is manufactured by Jiangxi Alpha Hi-tech, a specialized manufacturer of high-performance pharmaceutical excipients in China with internationally compliant quality management systems. The product is available in a wide viscosity range from 50 – 12500 mm²/s, providing formulation flexibility across various dosage forms and applications.

2. Active ingredient of Dimethicone

• Active ingredient name: Dimethicone
• Chemical class: Siloxane polymer
• Chemical name: Polydimethylsiloxane
• Appearance: Clear, colorless to pale yellow liquid
• Viscosity range: 50 – 12500 mm²/s
• Characteristics: Hydrophobic, chemically inert, thermally stable
• Quality standards: USP/NF, EP, BP, JP, CP
• Certifications: EXCiPACT GMP, ISO 9001, Halal, Kosher

Dimethicone demonstrates excellent chemical and physical stability with strong resistance to oxidation and degradation under standard storage conditions, making it highly suitable for formulations requiring extended shelf life.

3. Key advantages of Dimethicone 

• Excellent biological inertness and superior safety profile: Dimethicone is minimally absorbed through the skin or mucosal membranes, non-toxic, and associated with very low irritation potential, making it highly suitable for pharmaceutical and cosmetic formulations requiring a high safety margin.
• Efficient antifoaming performance in complex formulation systems: Due to its surface tension-reducing properties, Dimethicone effectively controls foam generation during both manufacturing and product application, particularly in liquid and suspension systems.
• Superior protective film-forming and moisture retention capability: Its hydrophobic nature enables Dimethicone to form a thin protective barrier on the skin surface, helping reduce transepidermal water loss and enhance moisturization performance in topical formulations.
• Smooth sensory profile without greasy residue: Dimethicone provides a silky, smooth, and non-sticky skin feel, significantly improving the sensory experience of premium cosmetic and personal care products.
• Outstanding chemical and physical stability: The material exhibits excellent resistance to oxidation and degradation under normal storage conditions while maintaining functional performance throughout the product lifecycle.
• Broad compatibility with excipient and active ingredient systems: Dimethicone demonstrates excellent compatibility with various oil phases, emulsions, and polymer systems commonly used in modern pharmaceutical and cosmetic formulations.
• Compliance with international pharmaceutical standards: The material complies with USP/EP/BP standards and is supported by EXCiPACT GMP certification, facilitating pharmaceutical product registration and export activities.
• Stable supply chain and comprehensive technical support: The product is readily available in GSP/GDP warehouses with complete documentation including COA, MSDS, TDS, and product specifications for industrial-scale manufacturing requirements.

4. Applications of Dimethicone

In pharmaceutical formulations

• Antifoaming oral solutions: Helps control foam generation during manufacturing and administration of oral liquid formulations.
• Tablets: Functions as a lubricant excipient to improve tablet compression performance and reduce processing friction.
• Hard capsules: Enhances powder flowability and improves capsule filling efficiency in industrial production.
• Topical creams: Forms a protective barrier on the skin surface, helping reduce transepidermal water loss and improve skin smoothness.
• Topical gels: Enhances formulation smoothness, reduces tackiness, and improves product sensory properties.
• Ointments: Improves spreadability and enhances the stability of semisolid formulation systems.
• Injectable formulations: Used as an antifoaming agent in selected specialized formulations requiring high purity standards.

 In cosmetic formulations

• Moisturizing creams: Provides moisture-locking effects and enhances skin softness.
• Facial serums: Delivers a silky skin feel, reduces stickiness, and improves user sensory experience.
• Sunscreen products:  Enhances spreading performance and improves lightweight skin feel.
• Makeup primers: Creates a smoothing effect on the skin surface and helps minimize the appearance of pores.
• Body lotions: Improves skin smoothness and helps reduce moisture loss.
• Hair care products: Forms a protective coating that improves softness, shine, and anti-frizz performance.

5. Commercial products using Dimethicone

6. Product contact information

For further information regarding Dimethicone supply capability, technical specifications, or commercial inquiries, please contact us:

• Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website: www.biorichgroup.com
• Sample & COA Request:  Please contact us via email to request product samples and the latest Certificate of Analysis (COA).