Copovidone – Premium Binder Excipient Optimized for Direct Compression

1. General introduction of Copovidone

Copovidone (Vinylpyrrolidone-vinyl acetate copolymer) is a linear, amorphous copolymer synthesized from N-vinylpyrrolidone (NVP) and vinyl acetate (VA) monomers in a precise 6:4 mass ratio. This engineered structure perfectly balances the superior hydrophilic binding capabilities of PVP (Polyvinylpyrrolidone) with the moisture-resistant, flexible properties of vinyl acetate. It is specifically designed to address critical formulation challenges in modern solid dosage forms, including tablet mechanical integrity and API bioavailability enhancement.

KoVidone VA64 is a premium commercial grade of copovidone, specifically engineered to meet stringent pharmaceutical standards and deliver consistent performance across advanced formulations.

2. Active composition of Copovidone

Typical technical specifications:

Chemical name:Polyvinylpyrrolidone-vinyl acetate copolymer
Molecular formula:(C6H9NO)n(C4H6O2)m
Appearance: is a white to yellowish-white amorphous powder.
Solubility: freely soluble in water, ethanol (95%)

3. Key advantages of Copovidone

Exceptional Binding Efficiency in Direct Compression: Due to its highly plastic deformation behavior, Copovidone creates robust intergranular bonds. This allows formulators to reduce excipient levels while achieving superior tablet hardness and eliminating capping or lamination issues.
Ideal Matrix for Hot-Melt Extrusion (HME): With an optimal glass transition temperature and high thermal stability, Copovidone is the gold standard carrier for solid dispersions, stabilizing poorly soluble APIs in an amorphous state to prevent recrystallization.
Lower Hygroscopicity and Enhanced Stability: The presence of hydrophobic vinyl acetate groups significantly decreases moisture sensitivity, protecting hydrolytically unstable APIs and extending product shelf-life.

4. Applications of Copovidone

In Pharmaceuticals:

Dry and Wet Binder: Suitable for direct compression formulations of conventional tablets and orally disintegrating tablets (ODTs). In addition, copovidone is widely used in both wet granulation and dry granulation processes for manufacturing high drug-load tablets.
Bioavailability Enhancement Carrier: Functions as the primary polymeric matrix in HME and Spray Drying technologies to improve the dissolution profiles of BCS Class II and IV drug
Film-forming agent: provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.

In Premium Cosmetics:

Film Former and Fixative: Employed in high-end hair styling products (sprays, gels) and waterproof mascaras, offering transparent, flexible films with excellent humidity resistance and zero stickiness.

5. Sample Copovidone Products

6. Product contact information

For more information about Copovidone sourcing, please contact us:

Nutra Hotline: +84 (0) 834 560 500
Email:biopharma@biorichpharma.com
Website: www.biorichpharma.com
Sample / COA Request: Please contact us via email to receive the latest sample and Certificate of Analysis (COA

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{"id":737392,"name":"Copovidone – Premium Binder Excipient Optimized for Direct Compression","desc":"Copovidone is a vinylpyrrolidone-vinyl acetate copolymer, widely used in pharmaceutical formulations as a dry binder, a matrix-forming excipient for modified-release dosage forms, and a film-forming agent for tablet coating.<\/span><\/p>","content":"<figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-03\/_Biorichgroup_com Product avatar site (19)(3).png\"><\/figure><h2 style=\"text-align:justify;\">1. General introduction of Copovidone<\/strong><\/span><\/h2>Copovidone<\/strong><\/span> (Vinylpyrrolidone-vinyl acetate copolymer) is a linear, amorphous copolymer synthesized from N-vinylpyrrolidone (NVP) and vinyl acetate (VA) monomers in a precise 6:4 mass ratio. This engineered structure perfectly balances the superior hydrophilic binding capabilities of PVP (Polyvinylpyrrolidone) with the moisture-resistant, flexible properties of vinyl acetate. It is specifically designed to address critical formulation challenges in modern solid dosage forms, including tablet mechanical integrity and API bioavailability enhancement.<\/span><\/p>KoVidone VA64<\/strong><\/span> is a premium commercial grade of copovidone, specifically engineered to meet stringent pharmaceutical standards and deliver consistent performance across advanced formulations.<\/span><\/p><h2 style=\"text-align:justify;\">2. Active composition of Copovidone&nbsp;<\/strong><\/span><\/h2>Typical technical specifications:<\/strong><\/span><\/p><ul><li>Chemical name: <\/span>Polyvinylpyrrolidone-vinyl acetate copolymer<\/strong><\/span><\/li><li>Molecular formula: <\/span>(C6H9NO)n(C4H6O2)m<\/strong><\/span><\/li><li>Appearance: is a white to yellowish-white amorphous powder.<\/strong><\/span><\/li><li>Solubility: freely soluble in water, ethanol (95%)<\/strong><\/span><\/li><\/ul><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-03\/Hình ảnh viết bài web (29).png\"><\/figure><h2 style=\"text-align:justify;\">3. Key advantages of Copovidone<\/strong><\/span><\/h2><ul><li style=\"text-align:justify;\">Exceptional Binding Efficiency in Direct Compression:<\/strong><\/span> Due to its highly plastic deformation behavior, Copovidone creates robust intergranular bonds. This allows formulators to reduce excipient levels while achieving superior tablet hardness and eliminating capping or lamination issues.<\/span><\/li><li style=\"text-align:justify;\">Ideal Matrix for Hot-Melt Extrusion (HME):<\/strong><\/span> With an optimal glass transition temperature and high thermal stability, Copovidone is the gold standard carrier for solid dispersions, stabilizing poorly soluble APIs in an amorphous state to prevent recrystallization.<\/span><\/li><li style=\"text-align:justify;\">Lower Hygroscopicity and Enhanced Stability: <\/strong><\/span>The presence of hydrophobic vinyl acetate groups significantly decreases moisture sensitivity, protecting hydrolytically unstable APIs and extending product shelf-life.<\/li><\/ul><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-03\/Hình ảnh viết bài web (28)(1).png\"><\/figure><h2 style=\"text-align:justify;\">4. Applications of Copovidone<\/strong><\/span><\/h2>In Pharmaceuticals:<\/strong><\/span><\/p><ul><li>Dry and Wet Binder: <\/strong><\/span>Suitable for direct compression formulations of conventional tablets and orally disintegrating tablets (ODTs). In addition, copovidone is widely used in both wet granulation and dry granulation processes for manufacturing high drug-load tablets.<\/li><li>Bioavailability Enhancement Carrier: <\/strong><\/span>Functions as the primary polymeric matrix in HME and Spray Drying technologies to improve the dissolution profiles of BCS Class II and IV drug&nbsp;<\/li><li style=\"text-align:justify;\">Film-forming agent:<\/strong><\/span> provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.<\/span><\/li><\/ul>In Premium Cosmetics:<\/strong><\/p><ul><li>Film Former and Fixative:<\/strong><\/span> Employed in high-end hair styling products (sprays, gels) and waterproof mascaras, offering transparent, flexible films with excellent humidity resistance and zero stickiness.<\/li><\/ul><h2 style=\"text-align:justify;\">5. Sample Copovidone Products&nbsp;<\/strong><\/span><\/h2><figure class=\"image image_resized\" style=\"width:75%;\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-03\/image(126).png\"><\/figure><h2 style=\"text-align:justify;\">6. Product contact information&nbsp;<\/strong><\/span><\/h2>For more information about&nbsp;<\/span>Copovidone&nbsp;<\/strong><\/span>sourcing, please contact us:<\/span><\/p><ul><li style=\"text-align:justify;\">Nutra Hotline:<\/strong> +84 (0) 834 560 500<\/span><\/li><li style=\"text-align:justify;\">Email:<\/strong> <\/span><a href=\"mailto:biopharma@biorichpharma.com\">biopharma@biorichpharma.com<\/span><\/a><\/li><li style=\"text-align:justify;\">Website:<\/strong><\/span><a href=\"http:\/\/www.biorichpharma.com\">&nbsp;<\/span>www.biorichpharma.com<\/u><\/span><\/a><\/li><li style=\"text-align:justify;\">Sample \/ COA Request: <\/strong>Please contact us via email to receive the latest&nbsp;sample and Certificate of Analysis (COA<\/strong><\/span><\/li><\/ul>&nbsp;<\/p>","image_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/images\/2026-03\/Copovidone%20-%20Avatar.png","image_thumb_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/thumb_images\/2026-03\/Copovidone%20-%20Avatar.png","tags":["copovidone","KoVidone VA64","pharmaceutical excipient","polymer VA64","tablet binder","excipient supplier","HotMelt Extrusion carrier","bioavailability enhancement"],"count_view":145,"seo_name":"copovidone-premium-excipient-enhancing-solubility-stability-and-therapeutic-performance","date_update":1773821400,"date_created_format":1773824663,"meta_title":"Copovidone – Premium Binder Excipient Optimized for Direct Compression","meta_desc":"Copovidone is a vinylpyrrolidone-vinyl acetate copolymer, widely used in pharmaceutical formulations as a dry binder, a matrix-forming excipient for modified-release dosage forms, and a film-forming agent for tablet coating.","meta_keyword":"Copovidone KoVidone VA64,premium pharmaceutical excipient,copovidone VA64 binder,solubility enhancement polymer,drug formulation excipient,bioavailability enhancer","qr_code":"https:\/\/www.biorichgroup.com\/copovidone-premium-excipient-enhancing-solubility-stability-and-therapeutic-performance","title_page":"Product","relate_object_id":737392,"company_logo":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/images\/logo\/Biorich%20Group%20Logo%20Final%20cuoi%20png.png","company_name":"Biorich Group","company_email":"director@biorichgroup.com","company_phone":"+84 834 560 500","company_address":"01 Pham Ngoc Thach Street, Sai Gon Ward, Ho Chi Minh City 70000, Vietnam","company_fax":"","date_now":1783498740,"company_tags":["Biorich","Biopharma","Pharma","Nutra","Cosmetics","Food","Veterinary","Lab chemicals","Packaging","Machinery","Logistics","Seafood","Aquaculture","Agriculture"],"search_keyword":null,"facebook_comment":"https:\/\/www.biorichgroup.com\/copovidone-ta-duoc-dinh-cao-cap-toi-uu-cho-quy-trinh-dap-thang","breadscrumb":[{"url":"https:\/\/www.biorichgroup.com","name":"Home","icon":"","active":false},{"url":"https:\/\/www.biorichgroup.com\/product-information","name":"Product Information","icon":"","active":true}],"list_products_tmp":[],"list_section":[{"id":721611,"name":"SECTION-261012","seo_name":"#w30s-section-721611","url":"#w30s-section-721611"},{"id":724344,"name":"SECTION-261064","seo_name":"#w30s-section-724344","url":"#w30s-section-724344"},{"id":722390,"name":"SECTION-263578","seo_name":"#w30s-section-722390","url":"#w30s-section-722390"}],"type_page":7,"id_page":512269,"widget_16921158":{"content_data":{"content":"Search"}},"widget_16416610":{"content_data":{"content":"Menu"}},"widget_16921159":{"content_data":[]},"widget_16921161":{"content_data":{"content":"Search"}},"widget_16921162":{"content_data":[{"id":125853,"title":"Tiếng Anh","code":"us","is_expires":false,"is_active":0},{"id":125852,"title":"Tiếng Việt","code":"vn","is_expires":false,"is_active":1}]},"widget_16416615":{"content_data":[{"id":125853,"title":"Tiếng Anh","code":"us","is_expires":false,"is_active":0},{"id":125852,"title":"Tiếng Việt","code":"vn","is_expires":false,"is_active":1}]},"widget_16416613":{"content_data":{"content":"Menu"}},"widget_16348860":{"content_data":{"content":"RELATED ARTICLES"}},"widget_16348866":{"content_data":[{"id":749853,"name":"Sodium Borate – High-quality buffering and emulsifying excipient from India","desc":"Sodium Borate from Sujata Nutri-Pharma Pvt. Ltd. A premium pharmaceutical excipient acting as a specialized pH buffer and emulsifier for ointments, creams, and solutions. Contact Biorich now!<\/p>","content":"<figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/Sodium Borate – Tá dược đệm và nhũ hóa chất lượng cao từ Ấn Độ(1).jpg\"><\/figure><h2>1. General Introduction to Sodium Borate<\/h2>Sodium Borate (also known as Borax) is an inorganic salt commonly used in the pharmaceutical and cosmetic industries. Its primary function is to act as a pH buffering agent, a mild alkalizing agent, and particularly an effective emulsifier when combined with beeswax to create stable cream and ointment formulations.<\/p>The raw material is manufactured by Sujata Nutri-Pharma Pvt. Ltd., a reputable pharmaceutical chemical manufacturer in India. With a strict quality management system, Sujata's Sodium Borate achieves high purity, meeting the most rigorous standards for application in medical and healthcare products.<\/p><h2>2. Raw Material Information for Sodium Borate<\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/2(21).png\"><\/figure><ul><li>Material Name<\/strong><\/span>:<\/strong> Sodium Borate (Borax)<\/li><li>Manufacturer<\/strong><\/span>:<\/strong> Sujata Nutri-Pharma Pvt. Ltd.<\/li><li>Origin<\/strong><\/span>:<\/strong> India<\/li><li>Material Category<\/strong><\/span>:<\/strong> Pharmaceutical excipient \/ Buffering agent, emulsifier.<\/li><li>Function<\/strong><\/span>:<\/strong> Adjusts pH, creates emulsion systems (when combined with beeswax), mild preservative.<\/li><li>Chemical Formula<\/strong><\/span>:<\/strong> Na2B4O7·10H2O.<\/li><li>Form<\/strong><\/span>:<\/strong> White crystalline powder, odorless.<\/li><li>Solubility<\/strong><\/span>:<\/strong> Freely soluble in water and glycerin, insoluble in alcohol.<\/li><li>Quality Standard<\/strong><\/span>:<\/strong> Complies with current international Pharmacopoeia standards.<\/li><li>The material is strictly controlled for heavy metal and impurity limits, ensuring maximum safety for users when formulated into pharmaceutical products.<\/li><\/ul><h2>3. Advantages of Sodium Borate from Sujata Nutri-Pharma<\/h2><ul><li>High purity<\/strong><\/span>:<\/strong> Ensures the stability of the pH buffering system throughout the shelf life of the finished product.<\/li><li>Excellent emulsifying ability<\/strong><\/span>:<\/strong> When combined with beeswax, it creates highly homogeneous emulsion systems, increasing the smoothness and sensory feel of topical creams.<\/li><li>Safety and compatibility<\/strong><\/span>:<\/strong> Compatible with a wide range of active ingredients in solution and ointment formulations.<\/li><li>Reasonable cost - Stable supply<\/strong><\/span>:<\/strong> Manufactured in India by Sujata Nutri-Pharma, helping to optimize raw material costs while ensuring quality standards.<\/li><\/ul><h2>4. Applications of Sodium Borate<\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/3(21).png\"><\/figure><h3>In Pharmaceuticals and Cosmetics<\/strong><\/h3><ul><li>Topical ointments and creams<\/strong><\/span>:<\/strong> Acts as an emulsifier (combined with beeswax) and buffering agent in therapeutic creams, cold creams, lotions, and topical ointments.<\/li><li>Topical solutions<\/strong><\/span>:<\/strong> Acts as a pH buffer to make solutions mild and non-irritating to mucous membranes (used at permitted concentrations).<\/li><li>Skincare products<\/strong><\/span>:<\/strong> Applied in cleansing creams, lotions, and other cosmetic formulations thanks to its mild antibacterial and alkalizing properties.<\/li><\/ul><h2>5. Commercial Products Using Sodium Borate<\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/4(21).png\"><\/figure><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/5(21).png\"><\/figure><h2>6. Product Contact Information<\/h2>For more information about the supply chain, technical specifications of Sodium Borate, or to place an order, please contact us:<\/p><ul><li>Consulting Hotline:<\/strong> +84 (0) 834 560 500<\/li><li>Email:<\/strong> director@biorichgroup.com<\/li><li>Website:<\/strong> <a href=\"https:\/\/www.biorichgroup.com\">www.biorichgroup.com<\/a><\/li><li>Sample\/COA Request:<\/strong> Please contact us via email to request samples and the latest Certificate of Analysis (COA) for the raw material from the manufacturer Sujata Nutri-Pharma Pvt. Ltd.<\/li><\/ul>","image_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20Borate%20%E2%80%93%20T%C3%A1%20d%C6%B0%E1%BB%A3c%20%C4%91%E1%BB%87m%20v%C3%A0%20nh%C5%A9%20h%C3%B3a%20ch%E1%BA%A5t%20l%C6%B0%E1%BB%A3ng%20cao%20t%E1%BB%AB%20%E1%BA%A4n%20%C4%90%E1%BB%99.jpg","image_thumb_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/thumb_images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20Borate%20%E2%80%93%20T%C3%A1%20d%C6%B0%E1%BB%A3c%20%C4%91%E1%BB%87m%20v%C3%A0%20nh%C5%A9%20h%C3%B3a%20ch%E1%BA%A5t%20l%C6%B0%E1%BB%A3ng%20cao%20t%E1%BB%AB%20%E1%BA%A4n%20%C4%90%E1%BB%99.jpg","tags":["Sodium Borate","Sujata NutriPharma","emulsifying excipient","pharmaceutical Sodium Borate","Sodium borate raw material"],"count_view":14,"seo_name":"sodium-borate-high-quality-buffering-and-emulsifying-excipient-from-india","date_update":1783505940,"date_created_format":1783419998,"meta_title":"Sodium Borate","meta_desc":"Sodium Borate from Sujata Nutri-Pharma Pvt. Ltd. A premium pharmaceutical excipient acting as a specialized pH buffer and emulsifier for ointments, creams, and solutions. Contact Biorich now!","meta_keyword":"Sodium Borate,Sujata NutriPharma,emulsifying excipient,pharmaceutical Sodium Borate,Sodium borate raw material","qr_code":"https:\/\/www.biorichgroup.com\/sodium-borate-high-quality-buffering-and-emulsifying-excipient-from-india"},{"id":749843,"name":"Sodium bisulfite CDMF PARENTEX PLUS – Premium antioxidant excipient from India","desc":"Sodium bisulfite CDMF PARENTEX PLUS from Aceto Pharma (India) Pvt Ltd. A premium pharmaceutical excipient acting as a specialized antioxidant for injectables and aqueous solutions. Contact Biorich now!<\/p>","content":"<figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/Sodium bisulfite CDMF PARENTEX PLUS – Tá dược chống oxy hóa cao cấp từ Ấn Độ(1).jpg\"><\/figure><h2>1. General Introduction to Sodium bisulfite CDMF PARENTEX PLUS<\/h2>Sodium bisulfite is an inorganic compound with strong reducing pr operties, widely used as an antioxidant in the pharmaceutical industry. Its primary function is to protect oxidation-sensitive active ingredients, thereby maintaining stability, preventing discoloration, and extending product shelf life.<\/p>The raw material Sodium bisulfite CDMF PARENTEX PLUS is manufactured by Aceto Pharma (India) Pvt Ltd, a reputable manufacturer in India. With internationally standardized purification processes, this material possesses high purity, meeting the strictest standards for application in high-end medical products, especially parenteral dosage forms.<\/p><h2>2. Raw Material Information for Sodium bisulfite CDMF PARENTEX PLUS<\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/2(19).png\"><\/figure><ul><li>Material Name<\/strong><\/span>:<\/strong> Sodium bisulfite (CDMF PARENTEX PLUS grade)<\/li><li>Manufacturer<\/strong><\/span>:<\/strong> Aceto Pharma (India) Pvt Ltd<\/li><li>Origin<\/strong><\/span>:<\/strong> India<\/li><li>Material Category<\/strong><\/span>:<\/strong> Pharmaceutical excipient \/ Antioxidant, reducing agent.<\/li><li>Function<\/strong><\/span>:<\/strong> Prevents oxidation, protects the integrity of active ingredients in solutions.<\/li><li>Chemical Formula<\/strong><\/span>:<\/strong> NaHSO3.<\/li><li>Form<\/strong><\/span>:<\/strong> White or yellowish-white crystalline powder, with a slight characteristic odor of sulfur dioxide (SO2).<\/li><li>Solubility<\/strong><\/span>:<\/strong> Very soluble in water, slightly soluble in alcohol (ethanol).<\/li><li>Quality Standard<\/strong><\/span>:<\/strong> Complies with current international Pharmacopoeia standards.<\/li><\/ul><h3>The material is strictly controlled for:<\/h3><ul><li>Impurity and heavy metal limits<\/strong><\/span>:<\/strong> Strictly controlled at extremely low levels, ensuring absolute safety when formulated into injectables administered directly into the bloodstream.<\/li><li>Endotoxin index<\/strong><\/span>:<\/strong> Specially purified for the \"Parentex\" line, with rigorous control of microbial and bacterial endotoxin limits.<\/li><\/ul><h2>3. Advantages of Sodium bisulfite from Aceto Pharma<\/h2><ul><li>High purity for injectables<\/strong><\/span>:<\/strong> The CDMF PARENTEX PLUS grade is optimized for physicochemical properties to ensure absolute safety for sterile preparations and intravenous injections.<\/li><li>Superior protection<\/strong><\/span>:<\/strong> Reacts preferentially with dissolved oxygen or free radicals, acting as a \"shield\" to protect easily degradable active ingredients (such as Epinephrine, Vitamin C, local anesthetics) from oxidation.<\/li><li>Excellent solubility<\/strong><\/span>:<\/strong> Easily integrated into aqueous solvent systems without negatively affecting the physical and mechanical properties of the finished product.<\/li><li>Reasonable cost - Stable supply<\/strong><\/span>:<\/strong> Manufactured by Aceto Pharma in India, offering competitive pricing advantages while maintaining the highest quality standards for manufacturing plants.<\/li><\/ul><h2>4. Applications of Sodium bisulfite CDMF PARENTEX PLUS<\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/3(19).png\"><\/figure><h3>In Pharmaceuticals (Core applications)<\/strong><\/h3><ul><li>Injections and infusions<\/strong><\/span>:<\/strong> Acts as the primary antioxidant in ampoules and vials containing active ingredients prone to oxidation or color change upon air exposure.<\/li><li>Eye drops and ear drops<\/strong><\/span>:<\/strong> Enhances the stability of sterile aqueous solutions throughout their shelf life.<\/li><li>Oral solutions<\/strong><\/span>:<\/strong> Protects active pharmaceutical ingredients in syrups or suspensions.<\/li><\/ul><h3>5. Commercial Products Using Sodium bisulfite<\/h3><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/4(19).png\"><\/figure><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/5(19).png\"><\/figure><h3>6. Product Contact Information<\/h3>For more information about the supply chain, technical specifications of Sodium bisulfite CDMF PARENTEX PLUS, or to place an order, please contact us:<\/p><ul><li>Consulting Hotline:<\/strong> +84 (0) 834 560 500<\/li><li>Email:<\/strong> director@biorichgroup.com<\/li><li>Website:<\/strong> <a href=\"https:\/\/www.biorichgroup.com\">www.biorichgroup.com<\/a><\/li><li>Sample\/COA Request:<\/strong> Please contact us via email to request samples and the latest Certificate of Analysis (COA) for the raw material from the manufacturer Aceto Pharma (India) Pvt Ltd.<\/li><\/ul>","image_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20bisulfite%20CDMF%20PARENTEX%20PLUS%20%E2%80%93%20T%C3%A1%20d%C6%B0%E1%BB%A3c%20ch%E1%BB%91ng%20oxy%20h%C3%B3a%20cao%20c%E1%BA%A5p%20t%E1%BB%AB%20%E1%BA%A4n%20%C4%90%E1%BB%99.jpg","image_thumb_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/thumb_images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20bisulfite%20CDMF%20PARENTEX%20PLUS%20%E2%80%93%20T%C3%A1%20d%C6%B0%E1%BB%A3c%20ch%E1%BB%91ng%20oxy%20h%C3%B3a%20cao%20c%E1%BA%A5p%20t%E1%BB%AB%20%E1%BA%A4n%20%C4%90%E1%BB%99.jpg","tags":["Sodium bisulfite CDMF PARENTEX PLUS","Aceto Pharma India","antioxidant excipient","pharmaceutical Sodium bisulfite","premium Sodium bisulfite raw material"],"count_view":13,"seo_name":"sodium-bisulfite-cdmf-parentex-plus-premium-antioxidant-excipient-from-india","date_update":1783501380,"date_created_format":1783415080,"meta_title":"Sodium bisulfite CDMF PARENTEX PLUS","meta_desc":"Sodium bisulfite CDMF PARENTEX PLUS from Aceto Pharma (India) Pvt Ltd. A premium pharmaceutical excipient acting as a specialized antioxidant for injectables and aqueous solutions. Contact Biorich now!","meta_keyword":"Sodium bisulfite CDMF PARENTEX PLUS,Aceto Pharma India,antioxidant excipient,pharmaceutical Sodium bisulfite,premium Sodium bisulfite raw material","qr_code":"https:\/\/www.biorichgroup.com\/sodium-bisulfite-cdmf-parentex-plus-premium-antioxidant-excipient-from-india"},{"id":749784,"name":"Sodium acetate trihydrate IP\/BP PARENTEX PLUS – International standard pH buffering excipient and electrolyte supplement from India","desc":"Premium injection-grade Sodium acetate trihydrate IP\/BP PARENTEX PLUS raw material from Aceto Pharma (India) Pvt Ltd. The optimal solution as a pH buffering agent and for use in hemodialysis solutions. Contact Biorich today!<\/p>","content":"<figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/Sodium acetate trihydrate IPBP PARENTEX PLUS.jpg\"><\/figure><h2>1. General Introduction to Sodium acetate trihydrate IP\/BP PARENTEX PLUS<\/strong><\/h2>Sodium acetate trihydrate is the sodium salt of acetic acid with three water molecules, playing a crucial role in the pharmaceutical and medical industries. The PARENTEX PLUS product line features the highest purity grade, specifically designed to meet the stringent requirements of intravenous infusions and dialysis solutions.<\/p>The raw material is manufactured by Aceto Pharma (India) Pvt Ltd,<\/strong><\/span> a reputable pharmaceutical chemical and excipient manufacturer in India with GMP certification. Aceto Pharma's Sodium acetate trihydrate is rigorously refined, ensuring the complete removal of bacterial endotoxins and impurities, meeting British Pharmacopoeia (BP) and Indian Pharmacopoeia (IP) standards.<\/p><h2>2. Sodium acetate trihydrate IP\/BP PARENTEX PLUS Raw Material Information<\/strong><\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/2(17).png\"><\/figure><ul><li>Material Name<\/strong><\/span>:<\/strong> Sodium acetate trihydrate PARENTEX PLUS<\/li><li>Manufacturer<\/strong><\/span>:<\/strong> Aceto Pharma (India) Pvt Ltd<\/li><li>Origin<\/strong><\/span>:<\/strong> India<\/li><li>Material Group<\/strong><\/span>:<\/strong> Excipients \/ Active Pharmaceutical Ingredient (API).<\/li><li>Function<\/strong><\/span>:<\/strong> pH buffering agent, systemic alkalinizer, source of sodium ions, parenteral excipient.<\/li><li>Chemical Composition<\/strong><\/span>:<\/strong> CH3COONa·3H2O.<\/li><li>Physical Form<\/strong><\/span>:<\/strong> Colorless crystals or white crystalline powder, may have a faint odor of acetic acid, very soluble in water.<\/li><li>Quality Standards<\/strong><\/span>:<\/strong> Meets Indian Pharmacopoeia (IP) and British Pharmacopoeia (BP) standards.<\/li><\/ul>The material is strictly controlled for:<\/strong><\/span><\/p><ul><li>Bacterial Endotoxins<\/strong><\/span>:<\/strong> Controlled at extremely low levels, meeting the strictest standards for the production of injections and intravenous fluids.<\/li><li>Heavy Metal Limits (Aluminum, Arsenic, Lead)<\/strong><\/span>:<\/strong> Ensures absolute purity, safe for the circulatory system when used in hemodialysis or intravenous fluids.<\/li><\/ul><h2>3. Advantages of Aceto Pharma's Sodium acetate trihydrate<\/strong><\/h2><ul><li>Superior PARENTEX PLUS Quality<\/strong><\/span>:<\/strong> This is a parenteral grade raw material with significantly higher biological and chemical purity than regular excipients, ensuring absolute safety when introduced directly into the bloodstream.<\/li><li>Excellent pH Buffering Capacity<\/strong><\/span>:<\/strong> Provides optimal pH stability for pharmaceutical solutions, preventing the degradation of pH-sensitive active ingredients.<\/li><li>Perfect Solubility<\/strong><\/span>:<\/strong> Dissolves completely and extremely fast in water, creating a clear solution with no suspended particles, ideal for manufacturing injectables.<\/li><li>High-Quality Supply<\/strong><\/span>:<\/strong> Manufactured directly at Aceto Pharma's facility in India, ensuring clear traceability, accurate COAs, and competitive pricing for industrial-scale production.<\/li><\/ul><h2>4. Applications of Sodium acetate trihydrate IP\/BP PARENTEX PLUS<\/strong><\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/3(17).png\"><\/figure><h4>In Pharmaceuticals (Core Application)<\/strong><\/h4><ul><li>Intravenous fluids<\/strong><\/span>:<\/strong> Used as a source of Sodium ions and acts as an alkalinizer to treat metabolic acidosis.<\/li><li>Hemodialysis solutions<\/strong><\/span>:<\/strong> An essential component in artificial kidney dialysis fluids, helping to balance electrolytes and control blood pH in patients with kidney failure.<\/li><li>Injections and eye drops<\/strong><\/span>:<\/strong> Acts as a buffering agent to adjust and maintain a stable pH environment for biological active ingredients, injectable antibiotics, or ophthalmic drugs.<\/li><\/ul><h4>In other Health and Food sectors<\/strong><\/h4><ul><li>Used as a preservative and acidity regulator in certain specialized healthcare products due to its bacteria-inhibiting properties.<\/li><\/ul><h2>5. Commercial Products Using Sodium acetate trihydrate<\/strong><\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/4(17).png\"><\/figure><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/5(17).png\"><\/figure><h2>6. Product Contact Information<\/strong><\/h2>For more information on the supply chain, technical specifications of Sodium acetate trihydrate IP\/BP PARENTEX PLUS,<\/strong><\/span> or to place an order, please contact us:<\/p><ul><li>Consultation Hotline:<\/strong> +84 (0) 834 560 500<\/li><li>Email:<\/strong> director@biorichgroup.com<\/li><li>Website:<\/strong> <a href=\"https:\/\/www.biorichgroup.com\">www.biorichgroup.com<\/a><\/li><li>Sample\/COA Request:<\/strong> Please contact us via email to request a sample and the latest Certificate of Analysis (COA) for the raw material from the manufacturer Aceto Pharma (India) Pvt Ltd.<\/li><\/ul>","image_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20acetate%20trihydrate%20IPBP%20PARENTEX%20PLUS.jpg","image_thumb_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/thumb_images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20acetate%20trihydrate%20IPBP%20PARENTEX%20PLUS.jpg","tags":["Sodium acetate trihydrate IPBP","PARENTEX PLUS excipient","parenteral excipient","Aceto Pharma Sodium acetate","Indian infusion raw material"],"count_view":28,"seo_name":"sodium-acetate-trihydrate-ip-bp-parentex-plus-ta-duoc-dem-ph-va-bo-sung-dien-giai-chuan-quoc-te-tu-an-do","date_update":1783368720,"date_created_format":1783319317,"meta_title":"Sodium acetate trihydrate IP\/BP PARENTEX PLUS","meta_desc":"Premium injection-grade Sodium acetate trihydrate IP\/BP PARENTEX PLUS raw material from Aceto Pharma (India) Pvt Ltd. The optimal solution as a pH buffering agent and for use in hemodialysis solutions. Contact Biorich today!","meta_keyword":"Sodium acetate trihydrate IPBP,PARENTEX PLUS excipient,parenteral excipient,Aceto Pharma Sodium acetate,Indian infusion raw material","qr_code":"https:\/\/www.biorichgroup.com\/sodium-acetate-trihydrate-ip-bp-parentex-plus-ta-duoc-dem-ph-va-bo-sung-dien-giai-chuan-quoc-te-tu-an-do"},{"id":749774,"name":"Sodium Bicarbonate – International standard effervescent excipient and antacid active ingredient from India","desc":"Premium Sodium Bicarbonate raw material from Sujata Nutri-Pharma Pvt. Ltd. (India). The optimal solution for generating effervescence in effervescent tablets and neutralizing stomach acid. Contact Biorich today!<\/p>","content":"<figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/Sodium Bicarbonate – Tá dược sủi bọt và Hoạt chất kháng axit chuẩn quốc tế từ Ấn Độ(1).jpg\"><\/figure><h2>1. General Introduction to Sodium Bicarbonate<\/strong><\/h2>Sodium Bicarbonate (NaHCO3) is a white, powdery inorganic compound that plays a vital role in the pharmaceutical industry. This active ingredient is widely applied as a gas-generating excipient in effervescent tablet and powder formulations, and as a common active pharmaceutical ingredient (API) to neutralize stomach acid and alkalinize the blood or urine.<\/p>The raw material is manufactured by Sujata Nutri-Pharma Pvt. Ltd. (India), a reputable pharmaceutical and excipient manufacturer with GMP certification. With a strictly controlled manufacturing process, Sujata's Sodium Bicarbonate achieves high purity and good free-flowing properties, fully meeting stringent international Pharmacopoeia standards.<\/p><h2>2. Sodium Bicarbonate Raw Material Information<\/strong><\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/2(15).png\"><\/figure><ul><li>Material Name<\/strong><\/span>:<\/strong> Sodium Bicarbonate<\/li><li>Manufacturer<\/strong><\/span>:<\/strong> Sujata Nutri-Pharma Pvt. Ltd.<\/li><li>Origin<\/strong><\/span>:<\/strong> India<\/li><li>Material Group<\/strong><\/span>:<\/strong> Excipients \/ Active Pharmaceutical Ingredient (API).<\/li><li>Function<\/strong><\/span>:<\/strong> Effervescent excipient, stomach antacid, alkalinizing agent, pH buffering agent.<\/li><li>Chemical Composition<\/strong><\/span>:<\/strong> NaHCO3.<\/li><li>Physical Form<\/strong><\/span>:<\/strong> White crystalline powder or crystals, odorless, with a slightly salty and alkaline taste.<\/li><li>Quality Standards<\/strong><\/span>:<\/strong> Meets United States Pharmacopeia (USP), European Pharmacopoeia (EP), or British Pharmacopoeia (BP) standards.<\/li><\/ul>The material is strictly controlled for:<\/strong><\/p><ul><li>Moisture and Particle Size<\/strong><\/span>:<\/strong> Ensures maximum stability for moisture-sensitive effervescent formulations.<\/li><li>Heavy Metals and Impurities Limits<\/strong><\/span>:<\/strong> Strict control of heavy metals and arsenic content, ensuring absolute safety for oral use and hemodialysis fluid preparation.<\/li><\/ul><h2>3. Advantages of Sujata's Sodium Bicarbonate<\/strong><\/h2><ul><li>Optimal CO2 Generating Capacity<\/strong><\/span>:<\/strong> Reacts quickly and completely with organic acids (such as citric and tartaric acid) when exposed to water, helping effervescent tablets dissolve rapidly to form a clear solution without leaving residue.<\/li><li>High Pharmaceutical Grade Purity<\/strong><\/span>:<\/strong> Meets API standards, safe for direct use as an antacid or in specialized medical solutions (such as dialysis fluid).<\/li><li>Excellent Formulation Characteristics<\/strong><\/span>:<\/strong> Evenly dispersed particles, easily homogenized in dry powder mixtures for effervescent tablet compression.<\/li><li>Reasonable Cost - Stable Supply<\/strong><\/span>:<\/strong> Manufactured in India by Sujata Nutri-Pharma, optimizing input material costs for pharmaceutical factories while maintaining international standards.<\/li><\/ul><h2>4. Applications of Sodium Bicarbonate<\/strong><\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/3(15).png\"><\/figure><h4>In Pharmaceuticals (Core Application)<\/strong><\/h4><ul><li>Effervescent tablet\/powder excipient<\/strong><\/span>:<\/strong> An indispensable ingredient in effervescent pain relievers, vitamin effervescent tablets, and fever-reducing effervescent powders.<\/li><li>Stomach medication (Antacid)<\/strong><\/span>:<\/strong> Serves as the main active ingredient to neutralize gastric acid, quickly relieving symptoms of heartburn, indigestion, and stomach ulcers.<\/li><li>Hemodialysis fluid<\/strong><\/span>:<\/strong> A crucial component in artificial kidney dialysis solutions to help balance electrolytes and blood pH.<\/li><\/ul><h4>In Health Supplements<\/strong><\/h4><ul><li>Nutritional supplement effervescent tablets:<\/strong> Applied as an effervescent excipient in Vitamin C, Multivitamin, mineral supplements, or effervescent energy drinks.<\/li><\/ul><h2>5. Commercial Products Using Sodium Bicarbonate<\/strong><\/h2><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/4(15).png\"><\/figure><figure class=\"image\"><img src=\"\/datafiles\/88336\/upload\/images\/2026-07\/5(15).png\"><\/figure><h2>6. Product Contact Information<\/strong><\/h2>For more information on the supply chain, technical specifications of Sodium Bicarbonate<\/strong><\/span>, or to place an order, please contact us:<\/p><ul><li>Consultation Hotline:<\/strong> +84 (0) 834 560 500<\/li><li>Email:<\/strong> director@biorichgroup.com<\/li><li>Website:<\/strong> <a href=\"https:\/\/www.biorichgroup.com\">www.biorichgroup.com<\/a><\/li><li>Sample\/COA Request:<\/strong> Please contact us via email to request a sample and the latest Certificate of Analysis (COA) for the raw material from the manufacturer Sujata Nutri-Pharma Pvt. Ltd.<\/li><\/ul>","image_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20Bicarbonate%20%E2%80%93%20T%C3%A1%20d%C6%B0%E1%BB%A3c%20s%E1%BB%A7i%20b%E1%BB%8Dt%20v%C3%A0%20Ho%E1%BA%A1t%20ch%E1%BA%A5t%20kh%C3%A1ng%20axit%20chu%E1%BA%A9n%20qu%E1%BB%91c%20t%E1%BA%BF%20t%E1%BB%AB%20%E1%BA%A4n%20%C4%90%E1%BB%99%281%29.jpg","image_thumb_url":"https:\/\/www.biorichgroup.com\/datafiles\/88336\/upload\/thumb_images\/Avatar%20s%E1%BA%A3n%20ph%E1%BA%A9m\/Sodium%20Bicarbonate%20%E2%80%93%20T%C3%A1%20d%C6%B0%E1%BB%A3c%20s%E1%BB%A7i%20b%E1%BB%8Dt%20v%C3%A0%20Ho%E1%BA%A1t%20ch%E1%BA%A5t%20kh%C3%A1ng%20axit%20chu%E1%BA%A9n%20qu%E1%BB%91c%20t%E1%BA%BF%20t%E1%BB%AB%20%E1%BA%A4n%20%C4%90%E1%BB%99%281%29.jpg","tags":["Sodium Bicarbonate","Sodium Bicarbonate excipient","effervescent excipient","Sodium Bicarbonate Sujata","Indian Sodium Bicarbonate raw material"],"count_view":23,"seo_name":"sodium-bicarbonate-international-standard-effervescent-excipient-and-antacid-active-ingredient-from-india","date_update":1783382820,"date_created_format":1783309336,"meta_title":"Sodium Bicarbonate","meta_desc":"Premium Sodium Bicarbonate raw material from Sujata Nutri-Pharma Pvt. Ltd. (India). The optimal solution for generating effervescence in effervescent tablets and neutralizing stomach acid. 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Copovidone – Premium Binder Excipient Optimized for Direct Compression

1. General introduction of Copovidone

2. Active composition of Copovidone

3. Key advantages of Copovidone

4. Applications of Copovidone

5. Sample Copovidone Products

6. Product contact information

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