Polacrilin Potassium – Specialized superdisintegrant and optimal taste-masking solution for tablets

1. General introduction to Polacrilin Potassium

Polacrilin Potassium (also known as Methacrylic acid polymer with Divinyl benzene with potassium form) is a highly versatile ion-exchange resin. In the pharmaceutical industry, this material is known as a new-generation superdisintegrant, possessing an extremely strong affinity for water.

The most outstanding feature of Polacrilin Potassium is its ability to hydrate and expand in volume immediately upon contact with a liquid medium without dissolving. This swelling force creates enormous internal pressure, rapidly breaking down the tablet or capsule structure, helping the active pharmaceutical ingredient to be released instantly and maximizing the product's bioavailability.

2. Information about Polacrilin Potassium

• Ingredient Name: Polacrilin Potassium
• Ingredient Group: Pharmaceutical Excipients / Superdisintegrant, Ion-exchange resin.
• Function: Superdisintegrant for fast tablet disintegration, taste masking, tablet structure stabilization.
• Chemical Composition: Cross-linked polymer of methacrylic acid and divinylbenzene as a potassium salt.
• Form: Free-flowing porous powder, white to off-white, no characteristic odor or taste.
• Solubility: Insoluble in water and most organic solvents, but possesses a very large volumetric swelling capacity when encountering water or gastrointestinal fluids.
• Quality Standards: Complies with strict current international Pharmacopoeia standards (USP/Ph.Eur/BP).

3. Advantages of the ingredient

• Outstanding superdisintegrant capability: Demonstrates excellent disintegration efficiency even when used at very low concentrations (usually only from 1% - 5%). The strong swelling force helps the tablet shatter immediately upon contact with water.
• Effective taste masking: Thanks to the cation-exchange mechanism, Polacrilin Potassium can reversibly bind to highly bitter active ingredients, preventing them from dissolving in saliva and perfectly masking unpleasant tastes.
• High safety and biological profile: As an insoluble polymer, this material is completely unabsorbed through the intestinal mucosa into the bloodstream. It travels through the digestive tract and is excreted intact, ensuring absolute safety for patients.
• High compatibility and stability: The material can be easily incorporated into direct compression, dry granulation, or wet granulation processes without causing chemical interactions with other ingredients, helping to maintain tablet hardness and stability.

4. Applications of Polacrilin Potassium

• In tablet and capsule manufacturing (Core application): Widely used as a superdisintegrant in conventional tablet formulas, hard capsules, and especially Fast Disintegrating Tablets (FDT).
• In chewables, lozenges, and suspensions: Plays an extremely important role as a taste-masking agent, especially in formulas containing antibiotics, syrups, or pediatric-specific medicines to increase treatment compliance.
• In controlled-release systems: Applied in specialized dosage forms (modified-release) to modify and control the release process of active ingredients at specific sites in the digestive tract.

5. Commercial products using Polacrilin Potassium

6. Product contact information

For more information about the supply chain and technical specifications of Polacrilin Potassium, or to receive a quote and place an order, please contact us:

• Consulting Hotline: +84 (0) 834 560 500
• Email: director@biorichgroup.com
• Website:www.biorichgroup.com
• Sample/COA Request: Please contact us via email to request a sample and the latest Certificate of Analysis (COA) for the ingredient.